BDBM50172198 2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-trien-6-yl-spiro[1H-indene-1,4'-(hexahydropyridine)]-1-ylmethanone::CHEMBL197265

SMILES C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)N1CCC2(CC1)C=Cc1ccccc21

InChI Key InChIKey=YOBSSBAJFVWQAA-CMYDWJSCSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172198   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172198(2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetrad...)
Affinity DataIC50:  750nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172198(2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetrad...)
Affinity DataEC50:  430nMAssay Description:Effective concentration in transactivation assay using a chimeric LXR construct in HEK293 cells for LXRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172198(2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetrad...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172198(2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetrad...)
Affinity DataEC50:  1.50E+3nMAssay Description:Effective concentration in recombinant human LXRbeta ligand binding domain in homogeneous time-resolved fluorescence assay More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed