BDBM50172198 2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-trien-6-yl-spiro[1H-indene-1,4'-(hexahydropyridine)]-1-ylmethanone::CHEMBL197265
SMILES C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)N1CCC2(CC1)C=Cc1ccccc21
InChI Key InChIKey=YOBSSBAJFVWQAA-CMYDWJSCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50172198
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 430nMAssay Description:Effective concentration in transactivation assay using a chimeric LXR construct in HEK293 cells for LXRalpha receptorMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.50E+3nMAssay Description:Effective concentration in recombinant human LXRbeta ligand binding domain in homogeneous time-resolved fluorescence assay More data for this Ligand-Target Pair