BDBM50172443 2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-morpholin-4-yl-quinolin-6-yl)-acetamide::CHEMBL196091

SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc12)N1CCOCC1

InChI Key InChIKey=JTQQWRBRIOITIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50172443   

TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172443(2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-morpholin-4...)
Affinity DataIC50:  15.4nMAssay Description:Inhibitory concentration against 10 nM MCH-induced IP3 accumulation in CHO-K1 cells expressing human MCH1R after incubation with [3H]-myo-inositolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172443(2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-morpholin-4...)
Affinity DataIC50:  5.5nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172443(2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-morpholin-4...)
Affinity DataIC50:  59nMAssay Description:Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed