BDBM50172771 1-(3,4-Difluoro-phenyl)-3-methyl-3-(3-methylamino-propyl)-3,4-dihydro-1H-quinolin-2-one::CHEMBL198011

SMILES CNCCCC1(C)Cc2ccccc2N(C1=O)c1ccc(F)c(F)c1

InChI Key InChIKey=OMMZYEKKLHJLJY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50172771   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50172771(1-(3,4-Difluoro-phenyl)-3-methyl-3-(3-methylamino-...)
Affinity DataKi:  77nMAssay Description:Inhibition of monoamine reuptake at norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50172771(1-(3,4-Difluoro-phenyl)-3-methyl-3-(3-methylamino-...)
Affinity DataKi: >100nMAssay Description:Inhibitio of monoamine reuptake at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50172771(1-(3,4-Difluoro-phenyl)-3-methyl-3-(3-methylamino-...)
Affinity DataKi: >200nMAssay Description:Inhibition of monoamine reuptake at dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed