BDBM50173129 CHEMBL3810104

SMILES Cc1cc(O)cc(C)c1C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O

InChI Key InChIKey=COJQNEGKUPBZCD-UHFFFAOYSA-N

Data  4 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50173129   

TargetMu-type opioid receptor(Guinea pig)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173129BDBM50173129(CHEMBL3810104)
Affinity DataIC50: 5.5nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-induced contraction by isometric force transducer a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173129BDBM50173129(CHEMBL3810104)
Affinity DataIC50: 13nMAssay Description:Agonist activity at delta opioid receptor in Swiss Webster albino mouse vas deferans assessed as inhibition of electrically-induced longitudinal musc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173129BDBM50173129(CHEMBL3810104)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in HEK293 cell membrane incubated for 1 hr by TopCount scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173129BDBM50173129(CHEMBL3810104)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in HEK293 cell membrane incubated for 1 hr by TopCount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173129BDBM50173129(CHEMBL3810104)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]OFQ/nociceptin from human nociceptin receptor expressed in HEK293 cell membrane incubated for 1 hr by TopCount scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173129BDBM50173129(CHEMBL3810104)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in HEK293 cell membrane incubated for 1 hr by TopCount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173129BDBM50173129(CHEMBL3810104)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human nociceptin receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed