BDBM50173531 1-(4-Hydroxy-5-triphenylsilanyloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione::CHEMBL197290::dUTPase inhibitor, 8
SMILES OC1CC(OC1CO[Si](c1ccccc1)(c1ccccc1)c1ccccc1)n1ccc(=O)[nH]c1=O
InChI Key InChIKey=HEOOHGVQTWVRSR-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50173531
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum (isolate 3D7))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 2.80E+3nM ΔG°: -7.57kcal/molepH: 8.0 T: 25°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 9.08E+5nM ΔG°: -4.15kcal/molepH: 8.0 T: 25°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
TargetdCTP deaminase(Campylobacter jejuni subsp. jejuni)
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 1.00E+9nM ΔG°: 0kcal/molepH: 8.0 T: 25°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair