BDBM50173554 CHEMBL194480::Hexadecanoic acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl ester::dUTPase inhibitor, 4
SMILES CCCCCCCCCCCCCCCC(=O)OCC1OC(C=C1)n1ccc(=O)[nH]c1=O
InChI Key InChIKey=GPPOEZFRRPLORQ-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50173554
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum (isolate 3D7))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 2.56E+5nM ΔG°: -4.90kcal/molepH: 8.0 T: 25°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum (isolate 3D7))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 2.56E+5nMAssay Description:Inhibitory constant against Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataKi: 3.50E+5nMAssay Description:Inhibitory constant against human deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataKi: 3.50E+5nM ΔG°: -4.71kcal/molepH: 8.0 T: 25°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory constant against Leishmania major deoxyuridine 5'-triphosphate nucleotidohydrolaseMore data for this Ligand-Target Pair
TargetdCTP deaminase(Campylobacter jejuni subsp. jejuni)
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 1.00E+9nM ΔG°: 0kcal/molepH: 8.0 T: 25°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair