BDBM50173563 1-{4-Fluoro-5-[(trityl-amino)-methyl]-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione::CHEMBL198660

SMILES O=c1ccn(C2CC(F)C(CNC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]1

InChI Key InChIKey=YQCHGQGDXXQRSN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173563   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum (isolate 3D7))
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173563BDBM50173563(1-{4-Fluoro-5-[(trityl-amino)-methyl]-tetrahydro-f...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibitory constant against Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetPutative deoxyuridine triphosphatase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173563BDBM50173563(1-{4-Fluoro-5-[(trityl-amino)-methyl]-tetrahydro-f...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory constant against Leishmania major deoxyuridine 5'-triphosphate nucleotidohydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50173563BDBM50173563(1-{4-Fluoro-5-[(trityl-amino)-methyl]-tetrahydro-f...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory constant against human deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed