BDBM50173576 1-[5-(Benzylamino-methyl)-4-hydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione::CHEMBL364710::dUTPase inhibitor, 11
SMILES OC1CC(OC1CNCc1ccccc1)n1ccc(=O)[nH]c1=O
InChI Key InChIKey=JFCBWRBGLGUNPH-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50173576
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum (isolate 3D7))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 1.11E+5nM ΔG°: -5.39kcal/molepH: 8.0 T: 25°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum (isolate 3D7))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 1.11E+5nMAssay Description:Inhibitory constant against Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory constant against Leishmania major deoxyuridine 5'-triphosphate nucleotidohydrolaseMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory constant against human deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataKi: 1.00E+6nM ΔG°: -4.09kcal/molepH: 8.0 T: 25°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
TargetdCTP deaminase(Campylobacter jejuni subsp. jejuni)
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 1.00E+9nM ΔG°: 0kcal/molepH: 8.0 T: 25°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair