BDBM50173688 3-[6-(3,4-Difluoro-phenyl)-pyridazin-4-yl]-benzonitrile::CHEMBL381670

SMILES Fc1ccc(cc1F)-c1cc(cnn1)-c1cccc(c1)C#N

InChI Key InChIKey=BKJDICAMUYQJHV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173688   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173688(3-[6-(3,4-Difluoro-phenyl)-pyridazin-4-yl]-benzoni...)
Affinity DataKi:  13nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173688(3-[6-(3,4-Difluoro-phenyl)-pyridazin-4-yl]-benzoni...)
Affinity DataKi:  41nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed