BDBM50174018 (E)-N-isopropyl-3-(3-(6-isopropylquinolin-8-yl)phenyl)-2-(4-(methylsulfonyl)phenyl)acrylamide::CHEMBL371089

SMILES CC(C)NC(=O)C(=C\c1cccc(c1)-c1cc(cc2cccnc12)C(C)C)\c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=JCWCKXNSHPKKEK-STBIYBPSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174018   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174018((E)-N-isopropyl-3-(3-(6-isopropylquinolin-8-yl)phe...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory activity against PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174018((E)-N-isopropyl-3-(3-(6-isopropylquinolin-8-yl)phe...)
Affinity DataIC50:  0.600nMAssay Description:Inhibitory activity against PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174018((E)-N-isopropyl-3-(3-(6-isopropylquinolin-8-yl)phe...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory activity against PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174018((E)-N-isopropyl-3-(3-(6-isopropylquinolin-8-yl)phe...)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed