BDBM50174031 (Z)-2-(4-(2-(3-(6-isopropylquinolin-8-yl)phenyl)-1-(4-(methylsulfonyl)phenyl)vinyl)phenyl)propan-2-ol::CHEMBL198674

SMILES CC(C)c1cc(-c2cccc(\C=C(\c3ccc(cc3)C(C)(C)O)c3ccc(cc3)S(C)(=O)=O)c2)c2ncccc2c1

InChI Key InChIKey=QHEUBKNOJMYNLT-HWIUFGAZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174031   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174031((Z)-2-(4-(2-(3-(6-isopropylquinolin-8-yl)phenyl)-1...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity against PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174031((Z)-2-(4-(2-(3-(6-isopropylquinolin-8-yl)phenyl)-1...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity against PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174031((Z)-2-(4-(2-(3-(6-isopropylquinolin-8-yl)phenyl)-1...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174031((Z)-2-(4-(2-(3-(6-isopropylquinolin-8-yl)phenyl)-1...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory activity against PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed