BDBM50174075 1-Pentanoylamino-4-phenyl-cyclohexanecarboxylic acid ((R)-1-{(S)-1-[(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide::CHEMBL199037::Penta-Apc-DPhe-Arg-Trp-NH2

SMILES CCCCC(=O)N[C@]1(C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)CC[C@H](c2ccccc2)CC1

InChI Key InChIKey=SQIYQDCUCZBAPA-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174075   

TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174075BDBM50174075(Penta-Apc-DPhe-Arg-Trp-NH2 | 1-Pentanoylamino-4-ph...)
Affinity DataEC50:  130nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174075BDBM50174075(Penta-Apc-DPhe-Arg-Trp-NH2 | 1-Pentanoylamino-4-ph...)
Affinity DataEC50:  130nMAssay Description:Agonist activity in HEK293 cells transfected with human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174075BDBM50174075(Penta-Apc-DPhe-Arg-Trp-NH2 | 1-Pentanoylamino-4-ph...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity in HEK293 cells transfected with human MC1R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174075BDBM50174075(Penta-Apc-DPhe-Arg-Trp-NH2 | 1-Pentanoylamino-4-ph...)
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed