BDBM50174168 CHEMBL3810121

SMILES Cc1nc2cccc3c2nc1NC/C=C\C[C@H]1CNC(=O)c2cc-3[nH]c21

InChI Key InChIKey=SMKDKOFQQMLFPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174168   

TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174168BDBM50174168(CHEMBL3810121)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human full-length Pim1 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser-112 preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174168BDBM50174168(CHEMBL3810121)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human full-length Pim2 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser 112 preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details Article
PubMed