BDBM50174240 CHEMBL197278::N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenylacetamido)methyl)cyclohexyl)piperazin-1-yl)propan-2-yl)indoline-2-carboxamide

SMILES Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3N2)C(=O)N2CCN(CC2)C2(CNC(=O)Cc3ccccc3)CCCCC2)cc1

InChI Key InChIKey=MKJINNZJGZZYPA-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174240   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174240(N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  210nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174240(N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataEC50:  360nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed