BDBM50174354 CHEMBL373294::[1-(2,5-Dichloro-benzenesulfonyl)-5-fluoro-2-methyl-1H-indol-3-yl]-acetic acid

SMILES Cc1c(CC(O)=O)c2cc(F)ccc2n1S(=O)(=O)c1cc(Cl)ccc1Cl

InChI Key InChIKey=DUFXUYDTVSRSQN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174354   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174354(CHEMBL373294 | [1-(2,5-Dichloro-benzenesulfonyl)-5...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174354(CHEMBL373294 | [1-(2,5-Dichloro-benzenesulfonyl)-5...)
Affinity DataKi:  1.87E+3nMAssay Description:Binding affinity towards human DP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174354(CHEMBL373294 | [1-(2,5-Dichloro-benzenesulfonyl)-5...)
Affinity DataIC50:  44nMAssay Description:Concentration required to inhibit PGD-2 (10 nM) stimulated [Ca2+] flux in CHO cells expressing human CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed