BDBM50174577 CHEMBL3810334

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)OCc1cc(=O)c(O)c[nH]1)OCc1ccccc1

InChI Key InChIKey=MNKUBDFRBLXMFB-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50174577   

TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174577BDBM50174577(CHEMBL3810334)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of tyrosinase (unknown origin) assessed as reduction in monophenolase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Zhejiang Gongshang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174577BDBM50174577(CHEMBL3810334)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate incubated for 10 mins by UV-Visible spectrophotometric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174577BDBM50174577(CHEMBL3810334)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of tyrosinase (unknown origin) assessed as reduction in monophenolase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174577BDBM50174577(CHEMBL3810334)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of tyrosinase (unknown origin) assessed as reduction in diphenolase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174577BDBM50174577(CHEMBL3810334)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of tyrosinase (unknown origin) assessed as reduction in diphenolase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Zhejiang Gongshang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174577BDBM50174577(CHEMBL3810334)
Affinity DataIC50: 8.97E+3nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by UV-Visible spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174577BDBM50174577(CHEMBL3810334)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of mushroom TyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Zhejiang Gongshang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174577BDBM50174577(CHEMBL3810334)
Affinity DataKi:  1.72E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-inhibitor complex incubated for 10 mins by Lin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Zhejiang Gongshang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174577BDBM50174577(CHEMBL3810334)
Affinity DataKi:  2.21E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-substrate-inhibitor complex incubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed