BDBM50175343 (4S,7S,11aS)-N-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)-6-oxo-7-(4-(trifluoromethyl)benzamido)-1,3,4,6,7,8,11,11a-octahydro-[1,4]oxazino[4,3-a]azocine-4-carboxamide::CHEMBL199784

SMILES OC1OC(=O)C[C@@H]1NC(=O)[C@@H]1COC[C@@H]2C\C=C/C[C@H](NC(=O)c3ccc(cc3)C(F)(F)F)C(=O)N12

InChI Key InChIKey=XWJCGBIHOVXIJS-VNAVJBQCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175343   

TargetCaspase-1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175343((4S,7S,11aS)-N-((3S)-2-hydroxy-5-oxo-tetrahydrofur...)
Affinity DataIC50:  135nMAssay Description:Inhibitory activity against Caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCaspase-8(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175343((4S,7S,11aS)-N-((3S)-2-hydroxy-5-oxo-tetrahydrofur...)
Affinity DataIC50:  6.45E+3nMAssay Description:Inhibitory activity against Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCaspase-3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175343((4S,7S,11aS)-N-((3S)-2-hydroxy-5-oxo-tetrahydrofur...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed