BDBM50175395 CHEMBL199965::N-(2,4-difluorobenzyl)-N-((4-(4-cyanobenzyl)-4H-1,2,4-triazol-3-yl)methyl)-2-naphthamide

SMILES Fc1ccc(CN(Cc2nncn2Cc2ccc(cc2)C#N)C(=O)c2ccc3ccccc3c2)c(F)c1

InChI Key InChIKey=VCUKCTLNWUDZBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175395   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50175395(CHEMBL199965 | N-(2,4-difluorobenzyl)-N-((4-(4-cya...)
Affinity DataIC50:  2.20nMAssay Description:Inhibitory activity against K-Ras farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed