BDBM50175398 CHEMBL381432::N-(4-bromophenethyl)-N-((4-(4-cyanobenzyl)-4H-1,2,4-triazol-3-yl)methyl)furan-2-carboxamide

SMILES Brc1ccc(CCN(Cc2nncn2Cc2ccc(cc2)C#N)C(=O)c2ccco2)cc1

InChI Key InChIKey=YSWNHCXNSHYSNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175398   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50175398(CHEMBL381432 | N-(4-bromophenethyl)-N-((4-(4-cyano...)
Affinity DataIC50:  99.3nMAssay Description:Inhibitory activity against K-Ras farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed