BDBM50175828 3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-(3-fluorophenyl)propanamide::CHEMBL200382

SMILES O=C(CCN1CCC(Cc2cnc[nH]2)CC1)Nc1cccc(F)c1

InChI Key InChIKey=XYJMAXNKTLJWRH-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175828   

TargetHistamine H3 receptor(Guinea pig)
The Schering Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175828BDBM50175828(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-(...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175828BDBM50175828(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-(...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in human brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175828BDBM50175828(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-(...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed