BDBM50176475 ((R)-5-cyano-6-fluoro-8-methyl-1-propyl-3,4-dihydro-1H-benzo[4,5]thieno[2,3-c]pyran-1-yl)-acetic acid::CHEMBL380997
SMILES CCC[C@]1(CC(O)=O)OCCc2c1sc1c(C)cc(F)c(C#N)c21
InChI Key InChIKey=XEPYXSNMTYAXLO-GOSISDBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50176475
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Displacement of [alpha-32P]GTP from recombinant HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataEC50: 3.20E+3nMAssay Description:Reduction of viral RNA and protein in Huh7 cells containing HCV sub-genomic repliconMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV reverse transcriptaseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibition of HCV NS3 helicaseMore data for this Ligand-Target Pair