BDBM50176906 CHEMBL219728::N'-(10H-indolo[3,2-b]quinolin-11-yl)-N,N-dimethylpropane-1,3-diamine::N-(3-(dimethylamino)propyl)-10H-indolo[3,2-b]quinolin-11-amine::N1-(10H-indolo[3,2-b]quinolin-11-yl)-N3,N3-dimethylpropane-1,3-diamine

SMILES CN(C)CCCNc1c2[nH]c3ccccc3c2nc2ccccc12

InChI Key InChIKey=CTDCVGDSVHUYMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50176906   

TargetTelomerase reverse transcriptase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50176906(CHEMBL219728 | N'-(10H-indolo[3,2-b]quinolin-11-yl...)
Affinity DataIC50:  630nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTelomerase reverse transcriptase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50176906(CHEMBL219728 | N'-(10H-indolo[3,2-b]quinolin-11-yl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed

TargetTelomerase reverse transcriptase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50176906(CHEMBL219728 | N'-(10H-indolo[3,2-b]quinolin-11-yl...)
Affinity DataIC50:  440nMAssay Description:Inhibition of telomerase derived from human K562 cell extract incubated for 30 mins by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetTelomerase reverse transcriptase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50176906(CHEMBL219728 | N'-(10H-indolo[3,2-b]quinolin-11-yl...)
Affinity DataIC50:  440nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed