BDBM50177902 CHEMBL3814484
SMILES CN1CCC(CC1)n1cc(cn1)-c1cnc(N)c(n1)-c1nc2ccccc2n1-c1cccc(NC(C)=O)c1
InChI Key InChIKey=YJEGLWNTKMTBGD-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50177902
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of wild-type EGFR autophosphorylation in human LoVo cells incubated for 2 hrs followed by EGF-stiumlation for 10 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of EGFR T790M/L858R double mutant autophosphorylation in human NCI-H1975 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 8.01E+3nMAssay Description:Inhibition of EGFR exon19 deletion activating mutant autophosphorylation in human PC9 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair