BDBM50178383 (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(methylsulfonyl)-1,2,3,4-tetrahydronaphthalen-1-amine::CHEMBL206211

SMILES CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccc(cc12)S(C)(=O)=O

InChI Key InChIKey=JSMCJJAIEPJIIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178383   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178383((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(methyls...)
Affinity DataIC50: 6nMAssay Description:Inhibition of serotonin re-uptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178383((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(methyls...)
Affinity DataIC50: 120nMAssay Description:Inhibition of dopamine re-uptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50178383((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(methyls...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of noradrenaline re-uptake at human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed