BDBM501784 4-[6-(3-aminopiperidin-1-yl)-4- methyl-3-(4-methylphenyl)-5-oxo- 4,5-dihydropyrazin-2- yl]benzonitrile::US11028066, Example 22

SMILES Cc1ccc(cc1)-c1c(nc(N2CCCC(N)C2)c(=O)n1C)-c1ccc(cc1)C#N

InChI Key InChIKey=KUZLABBZFDJWSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501784   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM501784(4-[6-(3-aminopiperidin-1-yl)-4- methyl-3-(4-methy...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent