BDBM50178402 (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-6-(methylsulfinyl)-1,2,3,4-tetrahydronaphthalen-1-amine::CHEMBL382241

SMILES CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2cc(ccc12)S(C)=O

InChI Key InChIKey=RBZDTFXHCQBMRR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178402   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178402((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-6-(methyls...)
Affinity DataIC50: 7nMAssay Description:Inhibition of serotonin re-uptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178402((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-6-(methyls...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of dopamine re-uptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50178402((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-6-(methyls...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of noradrenaline re-uptake at human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed