BDBM50178602 CHEMBL380342::N-((3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)-2-(1H-indol-3-yl)ethanamine

SMILES C(Cc1c[nH]c2ccccc12)NCC1CNc2ccccc2O1

InChI Key InChIKey=QUYCUSPRDZCQJY-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178602   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178602(CHEMBL380342 | N-((3,4-dihydro-2H-benzo[b][1,4]oxa...)
Affinity DataKi:  6.91nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178602(CHEMBL380342 | N-((3,4-dihydro-2H-benzo[b][1,4]oxa...)
Affinity DataKi:  89.8nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178602(CHEMBL380342 | N-((3,4-dihydro-2H-benzo[b][1,4]oxa...)
Affinity DataEC50:  93.5nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed