BDBM50178623 CHEMBL110365::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide

SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc-3c(Cc4ccccc-34)c2)CC1

InChI Key InChIKey=ZZFIFEVVRSMBSF-UHFFFAOYSA-N

Data  7 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50178623   

TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50178623(CHEMBL110365 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50178623(CHEMBL110365 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]spiroperidol from cloned human dopamine receptor D3 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50178623(CHEMBL110365 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  34nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50178623(CHEMBL110365 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  55.4nMAssay Description:Displacement of [125I]IABN from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50178623(CHEMBL110365 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  156nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50178623(CHEMBL110365 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  326nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50178623(CHEMBL110365 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  425nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50178623(CHEMBL110365 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataIC50:  224nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50178623(CHEMBL110365 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed