BDBM50178662 CHEMBL200056::acetic acid 2-[[(3S,4S)-4-(4-chlorophenyl)-1-methyl-piperidin-3-yl]methylsulfanyl]ethyl ester

SMILES CN1CC[C@@H]([C@H](CSCCOC(C)=O)C1)c1ccc(Cl)cc1

InChI Key InChIKey=NGCOVFQZQYNLNZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178662   

TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178662(acetic acid 2-[[(3S,4S)-4-(4-chlorophenyl)-1-methy...)
Affinity DataKi:  30nMAssay Description:Ability to inhibit [3H]NE uptake through NET in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178662(acetic acid 2-[[(3S,4S)-4-(4-chlorophenyl)-1-methy...)
Affinity DataKi:  46nMAssay Description:Ability to inhibit [3H]DA uptake through DAT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178662(acetic acid 2-[[(3S,4S)-4-(4-chlorophenyl)-1-methy...)
Affinity DataKi:  469nMAssay Description:Ability to inhibit [3H]5-HT uptake through SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed