BDBM50178663 2-[(3R,4R)-4-(4-chlorophenyl)-1-methylpiperidin-3-yl)methylsulfanyl]-N-methyl-acetamide::CHEMBL370830

SMILES CNC(=O)CSC[C@H]1CN(C)CC[C@H]1c1ccc(Cl)cc1

InChI Key InChIKey=LLLFWZQWZWPGBA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178663   

TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178663(2-[(3R,4R)-4-(4-chlorophenyl)-1-methylpiperidin-3-...)
Affinity DataKi:  5.5nMAssay Description:Ability to inhibit [3H]NE uptake through NET in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178663(2-[(3R,4R)-4-(4-chlorophenyl)-1-methylpiperidin-3-...)
Affinity DataKi:  215nMAssay Description:Ability to inhibit [3H]DA uptake through DAT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178663(2-[(3R,4R)-4-(4-chlorophenyl)-1-methylpiperidin-3-...)
Affinity DataKi:  1.77E+3nMAssay Description:Ability to inhibit [3H]5-HT uptake through SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed