BDBM50178672 (3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate::CHEMBL200252

SMILES COC(=O)[C@H]1CN(C)CC[C@H]1c1ccc(Cl)cc1

InChI Key InChIKey=GDFVYUDIAQQDTA-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50178672   

TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178672((3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidi...)
Affinity DataKi:  56nMAssay Description:Ability to inhibit [3H]5-HT uptake through SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50178672((3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidi...)
Affinity DataIC50: 195nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178672((3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidi...)
Affinity DataKi:  415nMAssay Description:Ability to inhibit [3H]NE uptake through NET in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50178672((3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidi...)
Affinity DataIC50: 653nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50178672((3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidi...)
Affinity DataKi:  1.56E+3nMAssay Description:Ability to inhibit [3H]DA uptake through DAT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed