BDBM50178762 1,6-bis-(Dmt-Tic-amino)hexane::CHEMBL197185

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCCCNC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C

InChI Key InChIKey=VJIXEMXKNBJTQB-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178762   

TargetDelta-type opioid receptor(Rat)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178762(1,6-bis-(Dmt-Tic-amino)hexane | CHEMBL197185)
Affinity DataKi:  0.129nMAssay Description:Displacement of [3H]deltorphin-II from delta opioid receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178762(1,6-bis-(Dmt-Tic-amino)hexane | CHEMBL197185)
Affinity DataKi:  1.79nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178762(1,6-bis-(Dmt-Tic-amino)hexane | CHEMBL197185)
Affinity DataIC50: 2.72E+3nMAssay Description:Agonistic activity at mu opioid receptor in myenteric plexus longitudinal muscle of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178762(1,6-bis-(Dmt-Tic-amino)hexane | CHEMBL197185)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonistic activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed