BDBM501788 4-[6-(4-aminopiperidin-1-yl)-4- ethyl-3-(4-methylphenyl)-5-oxo- 4,5-dihydropyrazin-2- yl]benzonitrile::US11028066, Example 26

SMILES CCn1c(-c2ccc(C)cc2)c(nc(N2CCC(N)CC2)c1=O)-c1ccc(cc1)C#N

InChI Key InChIKey=UHRVPYGFWCIOGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501788   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM501788(4-[6-(4-aminopiperidin-1-yl)-4- ethyl-3-(4-methyl...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent