BDBM50178961 CHEMBL2385268

SMILES CC1(C)CC=C(c2ccccc2)c2cc(\C=C\c3ccc(cc3)C(O)=O)ccc12

InChI Key InChIKey=VUODRPPTYLBGFM-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50178961   

TargetRetinoic acid receptor gamma(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at recombinant human RAR-gamma expressed in mammalian cells in presence of ATRA by luciferase reporter gene based transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRetinoic acid receptor beta(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at recombinant human RAR-beta expressed in mammalian cells by luciferase reporter gene based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha/alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]-TTNPB from RARalpha/RXRalpha (unknown origin) expressed in baculovirus expression system by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at recombinant human RAR-alpha expressed in mammalian cells in presence of 9-cis-RA by luciferase reporter gene based transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRetinoic acid receptor gamma(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataEC50:  120nMAssay Description:Agonist activity at recombinant human RAR-gamma expressed in mammalian cells by luciferase reporter gene based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataEC50:  200nMAssay Description:Inverse agonist activity at TLX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor gamma(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human RAR-gamma transfected in human HeLa cells co-transfected with RARE-CAT reporter gene assessed as inhibition of ATRA-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRetinoic acid receptor beta(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human RAR-beta transfected in human HeLa cells co-transfected with RARE-CAT reporter gene assessed as inhibition of ATRA-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human RAR-alpha transfected in human HeLa cells co-transfected with RARE-CAT reporter gene assessed as inhibition of ATRA-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRetinoic acid receptor beta(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at recombinant human RAR-beta expressed in mammalian cells in presence of ATRA by luciferase reporter gene based transactivation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed