BDBM50179142 (R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-cyclohexyl-4-(1,1-dioxo-1lambda*6*-isothiazolidin-2-ylmethyl)-piperidin-1-yl]-2-oxo-ethyl}-amide::CHEMBL203975
SMILES Clc1ccc(C[C@@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC(CN3CCCS3(=O)=O)(CC2)C2CCCCC2)cc1
InChI Key InChIKey=DTYOAGHBUMBHBH-FIRIVFDPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50179142
Affinity DataEC50: 540nMAssay Description:Activity against human MC3R by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 5.30nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.910nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 680nMAssay Description:Activity against human MC1BR by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 660nMAssay Description:Activity against human MC5R by cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1BR expressed in CHO cellsMore data for this Ligand-Target Pair