BDBM50179454 (S)-4,4-dimethyl-2-oxo-1-(2-(trifluoromethyl)-1,3,4-thiadiazole-5-carbonyl)pyrrolidin-3-yl (S)-1-(1H-pyrazol-5-ylamino)-1,2-dioxoheptan-3-ylcarbamate::CHEMBL383211

SMILES CCCC[C@H](NC(=O)O[C@@H]1C(=O)N(CC1(C)C)C(=O)c1nnc(s1)C(F)(F)F)C(=O)C(=O)Nc1ccn[nH]1

InChI Key InChIKey=LECXOAIUCLJFBA-GXFFZTMASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179454   

TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179454((S)-4,4-dimethyl-2-oxo-1-(2-(trifluoromethyl)-1,3,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed