BDBM50179466 (2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hydroxy-phenyl)-hexanoic acid [(S)-4-guanidino-1-((S)-1-methylcarbamoyl-2-naphthalen-2-yl-ethylcarbamoyl)-butyl]-amide::CHEMBL437132

SMILES CNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC[C@H](Cc1ccc(O)cc1)NC(C)=O)Cc1ccc(F)cc1

InChI Key InChIKey=GIHNRZCGDDBIDV-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50179466   

TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179466BDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataKi:  5nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179466BDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataEC50:  10nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179466BDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataKi:  6.20E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179466BDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataKi:  2.23E+4nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed