BDBM50181474 1-(3-benzyloxy-pyridin-2-yl)-3-(4-nitro-phenyl)-urea::CHEMBL203193

SMILES [O-][N+](=O)c1ccc(NC(=O)Nc2ncccc2OCc2ccccc2)cc1

InChI Key InChIKey=LVGIASYHZSVGII-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181474   

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50181474BDBM50181474(1-(3-benzyloxy-pyridin-2-yl)-3-(4-nitro-phenyl)-ur...)
Affinity DataIC50: 14nMAssay Description:Inhibition of isomerase activity of Cyclophilin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase F, mitochondrial(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50181474BDBM50181474(1-(3-benzyloxy-pyridin-2-yl)-3-(4-nitro-phenyl)-ur...)
Affinity DataIC50: 4.91E+3nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50181474BDBM50181474(1-(3-benzyloxy-pyridin-2-yl)-3-(4-nitro-phenyl)-ur...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed