BDBM501825 2-fluoro-4-[4-methyl-5-oxo-6- [((3S)-pyrrolidin-3-ylmethyl)- amino]-3-(4-trifluoromethoxy- phenyl)-4,5-dihydro-pyrazin-2-yl]- benzonitrile::US11028066, Example 63

SMILES Cn1c(-c2ccc(OC(F)(F)F)cc2)c(nc(NC[C@H]2CCNC2)c1=O)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=GXYJAMNVLXCFPP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501825   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM501825(2-fluoro-4-[4-methyl-5-oxo-6- [((3S)-pyrrolidin-3...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2021
Entry Details
US Patent