BDBM50182712 4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-1H-pyrazol-3-yl)-6-chlorobenzene-1,3-diol::4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL::4-chloro-6-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-1H-pyrazol-3-yl)benzene-1,3-diol::CHEMBL208239

SMILES CS(=O)(=O)c1ccc(CN2CCN(CC2)c2c[nH]nc2-c2cc(Cl)c(O)cc2O)cc1

InChI Key InChIKey=BDFJIEMVNDLSTB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50182712   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182712(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50:  740nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeat shock protein HSP 90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50182712(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50:  740nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182712(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed