BDBM50183563 CHEMBL3823697

SMILES COc1cc(cc(OC)c1CN(C)C)-c1cc(C)c(=O)n(C)c1C

InChI Key InChIKey=GQTWFQWDINXZPP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50183563   

TargetBromodomain-containing protein 9(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 57nMAssay Description:Inhibition of human N-terminal GST-tagged BRD9 isoform 1 expressed in Escherichia coli using tetra-acetylated histone H4 measured after 60 mins by Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 9(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 67nMAssay Description:Inhibition of amino terminal GST tagged BRD9 (aa 130-259 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 K9/14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain-containing protein 7(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 240nMAssay Description:Inhibition of human N-terminal GST-tagged BRD7 expressed in Escherichia coli using tetra-acetylated histone H4 measured after 60 mins by AlphaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 7(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 644nMAssay Description:Inhibition of BRD7 (unknown origin) using histone H3 K9/14/18/23Ac (1-28) peptide as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of human N-terminal GST-tagged BRD4-BD1 expressed in Escherichia coli using tetra-acetylated histone H4 measured after 60 mins by AlphaScr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of human N-terminal GST-tagged BRD2-BD1 expressed in Escherichia coli using tetra-acetylated histone H4 measured after 60 mins by AlphaScr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using acetylated H4 K5/8/12/16 as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal GST-tagged BRD4-BD2 expressed in Escherichia coli using tetra-acetylated histone H4 measured after 60 mins by AlphaScr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) using acetylated H4 K5/8/12/16 as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed