BDBM50184739 2-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethyl)pyridin-2-yl)-1,2,4,5,6,7-hexahydropyrazolo[3,4-b]pyridin-3-one::CHEMBL210527

SMILES O=c1c2c([nH]n1-c1ccc(C(F)(F)F)cc1)NC(c1ncccc1C(F)(F)F)CC2

InChI Key InChIKey=IFSKARVSVNXCMC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184739   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharp & Dohme

Curated by ChEMBL

LigandBDBM50184739(2-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethy...)Copy SMILESCopy InChI

Affinity DataIC50: 290nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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