BDBM50185408 (+/-)-(4aS,6R,8aS)-6-(4-chloro-benzenesulfonyl)-6-(2,5-difluoro-phenyl)-3-isopropyl-octahydro-benzo[1,2,6]thiadiazine 2,2-dioxide::CHEMBL207454

SMILES CC(C)N1C[C@@H]2C[C@](CC[C@@H]2NS1(=O)=O)(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=KIKHYLCLMBUGBG-UZQPLGKSSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185408   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Neuroscience Research Centre

Curated by ChEMBL

LigandBDBM50185408((+/-)-(4aS,6R,8aS)-6-(4-chloro-benzenesulfonyl)-6-...)Copy SMILESCopy InChI

Affinity DataIC50:  0.410nMAssay Description:Inhibition of gamma secretaseMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoCHEMBLPC cidPC sidSimilars

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