BDBM50185859 9a-butyl-7-hydroxy-4-phenyl-1,2,9,9a-tetrahydrofluoren-3-one::CHEMBL380469

SMILES CCCCC12Cc3cc(O)ccc3C1=C(C(=O)CC2)c1ccccc1

InChI Key InChIKey=JTOVSRDMFFEVOJ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185859   

TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185859(9a-butyl-7-hydroxy-4-phenyl-1,2,9,9a-tetrahydroflu...)
Affinity DataEC50:  5nMAssay Description:Activity at human ERbeta transfected in HEK293 cells assessed as transactivation of alkaline phosphatase reporter geneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185859(9a-butyl-7-hydroxy-4-phenyl-1,2,9,9a-tetrahydroflu...)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185859(9a-butyl-7-hydroxy-4-phenyl-1,2,9,9a-tetrahydroflu...)
Affinity DataIC50:  2nMAssay Description:Activity at human ERbeta transfected in HEK293 cells assessed as transactivation of alkaline phosphatase reporter geneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185859(9a-butyl-7-hydroxy-4-phenyl-1,2,9,9a-tetrahydroflu...)
Affinity DataIC50:  41nMAssay Description:Binding affinity to ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed