BDBM50185936 (2R,3R,4S,5S)-2-(6-(5-chloro-2-methoxybenzylamino)-9H-purin-9-yl)-4-(aminomethyl)-5-(hydroxymethyl)-tetrahydrofuran-3-ol::CHEMBL378069

SMILES COc1ccc(Cl)cc1CNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](CN)[C@H]1O

InChI Key InChIKey=SESOMNINYWTXPA-OZSDWXKXSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50185936   

TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185936((2R,3R,4S,5S)-2-(6-(5-chloro-2-methoxybenzylamino)...)
Affinity DataKi:  709nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor H272E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185936((2R,3R,4S,5S)-2-(6-(5-chloro-2-methoxybenzylamino)...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor H272D mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185936((2R,3R,4S,5S)-2-(6-(5-chloro-2-methoxybenzylamino)...)
Affinity DataKi:  9.80E+3nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor T94A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185936((2R,3R,4S,5S)-2-(6-(5-chloro-2-methoxybenzylamino)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor T94E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185936((2R,3R,4S,5S)-2-(6-(5-chloro-2-methoxybenzylamino)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor Q167E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185936((2R,3R,4S,5S)-2-(6-(5-chloro-2-methoxybenzylamino)...)
Affinity DataKi:  1.38E+4nMAssay Description:Displacement of [125I]I-AB-MECA from wild type adenosine A3 receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed