BDBM50186586 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1Hindol-4-yloxy)acetic acid::CHEMBL208429

SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc(C)cc2n1Cc1ccccc1

InChI Key InChIKey=IAUGVDTWTMEFGP-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50186586   

TargetPhospholipase A2, membrane associated(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  125nMAssay Description:Inhibition of mouse recombinant sPLA2 G2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant sPLA2 G2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of mouse recombinant sPLA2 G10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  850nMAssay Description:Inhibition of mouse recombinant sPLA2 G5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IIE secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  400nMAssay Description:Inhibition of mouse recombinant sPLA2 G2EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of mouse recombinant sPLA2 G1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human recombinant sPLA2 G10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IIE secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  125nMAssay Description:Inhibition of human recombinant sPLA2 G2EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant sPLA2 G5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50186586(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2,6-dimethyl-1...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant sPLA2 G1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed