BDBM50187383 CHEMBL207478::N-[3-(4-{4-[methyl-(2-methyl-propane-1-sulfonyl)-amino]-butyl}-piperazin-1-yl)-phenyl]-acetamide

SMILES CC(C)CS(=O)(=O)N(C)CCCCN1CCN(CC1)c1cccc(NC(C)=O)c1

InChI Key InChIKey=RSYFEHSGTZNRPM-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187383   

Target5-hydroxytryptamine receptor 1A(Human)
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50187383(N-[3-(4-{4-[methyl-(2-methyl-propane-1-sulfonyl)-a...)
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50187383(N-[3-(4-{4-[methyl-(2-methyl-propane-1-sulfonyl)-a...)
Affinity DataEC50:  32nMAssay Description:Activity against 5HT1A receptor by Gi-[35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50187383(N-[3-(4-{4-[methyl-(2-methyl-propane-1-sulfonyl)-a...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of hERG potassium channel in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed