BDBM50187785 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(dimethylamino)butanoyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL425783

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)CCCN(C)C)C(=O)NO

InChI Key InChIKey=KSOLTKWEALJMDR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50187785   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187785(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187785(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187785(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50:  7.97E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187785(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187785(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50:  177nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187785(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50:  302nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed