BDBM50188614 CHEMBL210964::N-n-pentyl-N'-[2-(4-methylphenylamino)-5-nitrobenzenesulfonyl]urea

SMILES CCCCCNC(=O)NS(=O)(=O)c1cc(ccc1Nc1ccc(C)cc1)[N+]([O-])=O

InChI Key InChIKey=ZXEYXJKZEQUHBP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188614   

TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188614(CHEMBL210964 | N-n-pentyl-N'-[2-(4-methylphenylami...)
Affinity DataIC50:  3.53nMAssay Description:Displacement of [3H]SQ29,548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188614(CHEMBL210964 | N-n-pentyl-N'-[2-(4-methylphenylami...)
Affinity DataIC50:  2.65nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188614(CHEMBL210964 | N-n-pentyl-N'-[2-(4-methylphenylami...)
Affinity DataIC50:  13.6nMAssay Description:Activity at TPbeta (long isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188614(CHEMBL210964 | N-n-pentyl-N'-[2-(4-methylphenylami...)
Affinity DataIC50:  50.0nMAssay Description:Activity at TPalpha (short isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188614(CHEMBL210964 | N-n-pentyl-N'-[2-(4-methylphenylami...)
Affinity DataIC50:  278nMAssay Description:Inhibition of U46619-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed