BDBM50188616 CHEMBL379659::N-n-pentyl-N'-[2-(3, 5-dimethylphenylamino)-5-nitrobenzenesulfonyl]urea

SMILES CCCCCNC(=O)NS(=O)(=O)c1cc(ccc1Nc1cc(C)cc(C)c1)[N+]([O-])=O

InChI Key InChIKey=DQRYGXUTHQISAW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50188616   

TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50188616(N-n-pentyl-N'-[2-(3, 5-dimethylphenylamino)-5-nitr...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50188616(N-n-pentyl-N'-[2-(3, 5-dimethylphenylamino)-5-nitr...)
Affinity DataIC50: 1.08nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50188616(N-n-pentyl-N'-[2-(3, 5-dimethylphenylamino)-5-nitr...)
Affinity DataIC50: 76.5nMAssay Description:Activity at TPbeta (long isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50188616(N-n-pentyl-N'-[2-(3, 5-dimethylphenylamino)-5-nitr...)
Affinity DataIC50: 538nMAssay Description:Activity at TPalpha (short isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed